GAIN-OF-FUNCTION, FOCAL SEGMENTAL GLOMERULOSCLEROSIS TRPC6 MUTATION MINIMALLY AFFECTS SUSCEPTIBILITY TO RENAL INJURY IN SEVERAL MOUSE MODELS

Gain-of-function, focal segmental glomerulosclerosis Trpc6 mutation minimally affects susceptibility to renal injury in several mouse models

Mutations in TRPC6 are a cause of autosomal dominant focal segmental glomerulosclerosis in humans.Many of these mutations are known to have a gain-of-function effect on the non-specific cation channel function of TRPC6.In vitro studies Bowl Drive Block have suggested these mutations affect several signaling pathways, but in vivo studies have largel

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Transcatheter Closure of Atrial Septal Defect in a Patient with Cor Triatriatum Sinister and Atrial Septal Defect

Cor triatriatum sinister is a rare congenital heart disease and rarely found in Hockey Protective - Gloves - Junior adults.The authors describe an asymptomatic 20-year old man presenting with heart murmur by check up.Transthoracic and transesophageal echocardiogram demonstrate atrial septal defect (ASD) secundum 26 mm and cor triatriatum sinister w

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Reproductive aspects of marine cladocerans Penilia avirostris and Pseudevadne tergestina (Crustacea, Branchiopoda) in the outer part of Guanabara Bay, Brazil

The objective Aronia of this study was to report on some aspects of marine cladoceran reproduction in Guanabara Bay.Samples were collected during 1985 using a conical net with 200 mm mesh.Two species were identified: Penilia avirostris and Pseudevadne tergestina.Both species disappeared from the plankton in winter.Two months before this phenomenon,

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